Coenzyme Q₁₀ is a powerful antioxidant that is involved in all the biochemical reactions in the body. It helps generate energy within the mitochondria (factories) of cells. It is found in every cell of the body but is present in higher concentrations in organs with greater energy demands such as the heart, liver, brain, kidneys and lungs. It is particularly important to maintain heart muscle cells and support the health of blood vessels.
Thanks to these two crucial functions, CoQ₁₀ helps maintain blood pressure already within normal limits,¹ supports the integrity of heart muscle,² increases circulation to the heart,³ improves exercise capacity, ⁴ ' ⁵ and supports a normal heart rhythm.*⁶ Additionally, it may protect against mild memory problems associated with aging. ⁷ ' ⁸ *
HyperIg Ubiquinol is the perfect nutritional supplement for anyone who wants to: decrease inflammation, protect cells from oxidative damage due to excessive free radicals, enhance exercise performance, reduce fatigue, support one’s heart, lung and brain, have healthy glucose utilization, maintain sperm and egg health, support skin's youthful appearance, and decrease headaches and migraines. Recent evidence suggests that supplementation with CoQ₁₀ may also be useful for supporting enhanced liver health.
People who are healthy can easily convert ubiquinone (the form of CoQ₁₀ featured in most supplements) to ubiquinol (the form used by the body to neutralize free radicals and create energy). But as we age, we produce less CoQ₁₀ and we become less efficient at converting ubiquinone to ubiquinol. By providing CoQ₁₀ already reduced to its ubiquinol form, as it is in the HyperIg Ubiquinol, the body is supplied with a more ready-to-use form of CoQ₁₀. It helps individuals increase and maintain their blood levels of CoQ₁₀.
One of the primary benefits of CoQ₁₀, particularly in the ubiquinol form featured in HyperIg Ubiquinol, is to provide antioxidant protection.* HyperIg Ubiquinol acts an electron donor, which means it can help neutralize unstable free radicals (oxidants) — without becoming a free radical itself.*
Certain medications, such as statins and certain conditions such as heart disease, can deplete CoQ₁₀ levels in the body. Supplementation with ubiquinol can restore CoQ₁₀ stores to normal levels. Additionally, some studies have concluded that supplementation with CoQ10 reduces muscle pain in individuals taking statins. ¹¹
Because of its role in energy production, CoQ₁₀ supports the functioning of organs with a high demand for energy, such as the heart and brain.* The heart muscle in particular is in constant need of a ready supply of energy to efficiently pump blood throughout the body. In fact, the majority of cardiac tissue is abundant in mitochondria requiring ample and consistent levels of CoQ₁₀ for proper functioning.*
Most people don’t eat enough foods containing CoQ₁₀ — such as fatty fish, organ meats, and whole grains — to raise blood levels of this vitamin-like essential nutrient. In fact, the average dietary intake of CoQ₁₀ is only 3-5 mg a day, much lower than what’ s needed to have any effect on CoQ₁₀ concentrations. Because ubiquinol is in a more bioavailable form, it has can increase levels of CoQ10 in the body more effectively than CoQ₁₀ by itself.
“Study on safety and bioavailability of ubiquinol after single and 4-week multiple oral administration to healthy volunteers.”
A single-blind placebo-controlled study published in Regulatory Toxicology and Pharmacology found that doses of up to 300 mg of ubiquinol were safe and bioavailable.
In the first phase of the study, ¹⁵ healthy subjects were administered a single dose of either 150 mg or 300 mg of Kaneka QHTM. The treatment:
A longer phase of the study followed 78 healthy subjects who took three different doses of Kaneka QHTM (90 mg, 150 mg, or 300 mg) or a placebo for 4 weeks.
The results showed that:
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
HyperIg Ubiquinol is a completely soluble, formulation, clinically demonstrated to be more absorbable by the body than conventional CoQ₁₀ products.
A completely soluble, 100% crystal-free formulation of CoQ₁₀ in the ubiquinol form, with clinically proven superior bioavailability.
¹ Yamagami T, et al. Bioenergetics in clinical medicine. Studies on coenzyme Q₁₀ and essential hypertension.
Res Commun Chem Pathol Pharmacol. 1975; 11:273.
² EBSCO Publishing. “Cardiomyopathy.” Consumerlab.com. Accessed June 9, 2009.
³ EBSCO Publishing. “Cardiomyopathy.” Consumerlab.com. Accessed June 9, 2009.
⁴ Kamikawa T, et al. Effects of coenzyme Q₁₀ on exercise tolerance in chronic stable angina pectoris. Am J Cardiol. 1985 Aug 1;56(4):247-51.
⁵ Wilson, M.R., et al. Coenzyme Q₁₀ therapy and exercise duration in stable angina. In: Folkers, K., Littami, G.P.,
Yamogami,T. (eds), Biomedical and Clinical Aspects of Coenzyme Q₁₀, vol. 6,Amsterdam. Elsevier;1991:339-348.
⁶ Singh RB, et al. Randomized double-blind placebo-controlled trial of coenzyme Q₁₀ in patients with acute myocardial infarction. Cardiovasc Drugs Ther. 1998;12:347-353.
⁷ Muller T, et al. Coenzyme Q₁₀ supplementation provides mild symptomatic benefit in patients with
Parkinson’s disease. Neurosci Lett. 2003;341:201-204.
⁸ Young AJ, et al. Coenzyme Q₁₀: A Promising Treatment for Alzheimer’s Disease? Abstr Academy Health Meet. 2004; 21: abstract no. 1715.
⁹ Not all CoQ₁₀ products are created equal. Insiders Health. Feb. 20, 2009.
¹⁰ Palamakula A et al. Preparation and in vitro characterization of self-nanoemulsified drug delivery systems of
coenzyme Q₁₀ using chiral essential oil components. Pharm Tech. 2004; 74.
¹¹ Skarlovnik, A, et al. Coenzyme Q10 supplementation decreases statin-related mild-to-moderate muscle symptoms: a randomized clinical study. Med Sci Monit. 2014;20:2183-2188.
Current literature suggests that CoQ10 is relatively safe with few drug interactions and side effects.
CAUTION: According to the Mayo Clinic, USA, CoQ10 may make blood-thinning drugs, such as warfarin (Coumadin, Jantoven), less effective. This could increase the risk of a blood clot. As with all supplements, if on prescription medications, consult with a health practitioner.
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Consult with a health professional before starting any diet, exercise or supplementation program. As with any nutritional supplement, always consult with a health professional if you are pregnant or nursing. Do not consume this whole egg protein if you have life-threatening reactions to egg.
Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.